MD, PhD, FRCP
I am Professor of Cancer Medicine and Lead of the Centre of Experimental Cancer Medicine at Barts Cancer Institute. I am Clinical Director of the St. Bartholomew Breast Cancer Centre and Honorary Consultant Medical Oncologist at Barts Hospital. I also lead the Cancer Immune Therapy group at Barts Hospital.
I studied medicine in Munich and Aberdeen. I was awarded scholarships by the German National Academic Foundation, the German Academic Exchange Service and the Hanns-Seidel-Foundation. I subsequently completed my specialist training in internal medicine, medical oncology and haematology in Berlin. I undertook an MD in Clinical Chemistry at the Technical University Munich and a PhD in Medical Oncology at the Charité University in Berlin. I moved to the UK in 2005 to take on roles as Senior Clinical Lecturer and Director of the Hammersmith Early Clinical Trials Unit at Imperial College London, and subsequently as Foundation Chair in Cancer Medicine at the University of Sussex.
I focus my clinical practice on breast cancer, lung cancer and cancer immune therapy. I led the formation of the Cancer Immune Therapy group at Barts Hospital which have become internationally-leading in this rapidly developing field. I have an international reputation for cancer immunotherapy and leads a number of global immunotherapy trials.
I have a particular research interest in triple negative breast cancer and endocrine resistance and have led more than 20 clinical studies and several translational research programmes in these areas. My interests lie in personalised cancer medicine utilising novel biomarkers (for example from bloods samples) and innovative, biomarker-driven clinical trial strategies to develop new treatment strategies. I lead an international group to establish blood-based circulating biomarkers.
I was awarded the Breast Cancer Research Award 2012 by German Patient group Mammazone.
I am a member of several national and international cancer organizations and research groups and have been involved in international consensus meetings on the management of breast cancer. I am a member of the breast cancer faculty of the European Society of Medical Oncology and have been chair or member of several medical research committees. I have authored or –co-authored more than 150 publications and have been an invited speaker and session chair at major European, North American Cancer and Asian cancer conferences. I have published a book on the management of bone metastases (3rd editions).
Outside my research areas, I have a strong interest in patient/doctor communication; for several years, I ran a programme to train oncologists and oncology nurses in communication skills supported by several patient groups.